HitPredict

Interactor 1: GPAA1 (O43292)
GPI-anchor transamidase component GPAA1 (GAA1 protein homolog) (hGAA1) (Glycosylphosphatidylinositol anchor attachment 1 protein) (GPI anchor attachment protein 1)
Gene: GPAA1

Interactor 2: GPI8 (Q92643)
GPI-anchor transamidase (EC 2.6.1.-) (GPI-anchor transamidase component PIGK, catalytic subunit) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)
Gene: PIGK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 12052837, 26186194, 28514442, 10793132, 33961781, 11483512, 12802054, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gaa1~Peptidase_C13
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0016255 - attachment of GPI anchor to protein
GO:0042765 - GPI-anchor transamidase complex
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 621
Hs

1 395
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025