HitPredict

Interactor 1: AP1G1 (O43747)
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
Gene: AP1G1

Interactor 2: AMPH (P49418)
Amphiphysin
Gene: AMPH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14973137
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048488 - synaptic vesicle endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 695
+	Hs
		321511 AP2A1_HUMAN (3-808): 0: 594: 24.39		AMPH_HUMAN (1-695): 5.58e-133: 409: 100.00
+	Hs
		302118 AP2A2_HUMAN (3-813): 0: 582: 24.55		AMPH_HUMAN (1-695): 5.58e-133: 409: 100.00
+	Hs
		827733 AP2B1_HUMAN (30-800): 0: 552: 16.59		AMPH_HUMAN (1-695): 5.58e-133: 409: 100.00
+	Mm
		567528 AP2A2_MOUSE (3-808): 0: 585: 24.70		AMPH_MOUSE (1-695): 5.33e-119: 373: 82.90
+	Hs
		827743 AP1B1_HUMAN (30-800): 0: 547: 17.36		AMPH_HUMAN (1-695): 5.58e-133: 409: 100.00
+	Rn
		88753 D3ZUY8_RAT (3-808): 0: 594: 24.68		AMPH_RAT (1-695): 6.91e-115: 362: 84.75
+	Rn
		139980 Q66HM2_RAT (3-808): 0: 584: 24.67		AMPH_RAT (1-695): 6.91e-115: 362: 84.75
+	Mm
		1186720 AP2B1_MOUSE (30-800): 0: 552: 16.59		AMPH_MOUSE (1-695): 5.33e-119: 373: 82.90
+	Rn
		139975 AP2B1_RAT (30-800): 0: 552: 16.59		AMPH_RAT (1-695): 6.91e-115: 362: 84.75
+	Rn
		88754 D3ZUY8_RAT (3-808): 0: 594: 24.68		BIN1_RAT (372-695): 8.26e-34: 139: 23.15
+	Hs
		131189 AP2A1_HUMAN (3-808): 0: 594: 24.39		BIN1_HUMAN (375-694): 1.37e-32: 135: 23.44
+	Rn
		139993 Q66HM2_RAT (3-808): 0: 584: 24.67		BIN1_RAT (372-695): 8.26e-34: 139: 23.15
+	Hs
		203194 AP2A1_HUMAN (3-808): 0: 594: 24.39		SYNJ1_HUMAN (187-647): 1.83e-28: 124: 11.70
+	Hs
		131185 AP2A2_HUMAN (3-813): 0: 582: 24.55		BIN1_HUMAN (375-694): 1.37e-32: 135: 23.44
+	Rn
		1144064 Q66HM2_RAT (3-808): 0: 584: 24.67		SYNJ1_RAT (186-667): 1.94e-25: 114: 13.82
+	Rn
		139988 AP2B1_RAT (30-800): 0: 552: 16.59		BIN1_RAT (372-695): 8.26e-34: 139: 23.15
+	Mm
		101412 AP1B1_MOUSE (30-800): 5.58e-180: 543: 16.83		F8VPR5_MOUSE (107-618): 2.01e-32: 137: 13.51
+	Hs
		203219 AP2B1_HUMAN (30-800): 0: 552: 16.59		SYNJ1_HUMAN (187-647): 1.83e-28: 124: 11.70
+	Hs
		203223 AP1B1_HUMAN (30-800): 0: 547: 17.36		SYNJ1_HUMAN (187-647): 1.83e-28: 124: 11.70
+	Hs
		1014106 AP1B1_HUMAN (30-800): 0: 547: 17.36		CABIN_HUMAN (291-589): 2.25e-12: 72.8: 12.87