Interactor 1: AP1G1 (O43747)
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
Gene: AP1G1

Interactor 2: AP1B1 (Q10567)
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Gene: AP1B1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.938

The method score is based on:

Property Details
Experiments 9733768, 33961781, 10535737, 7593184, 37071682, 10747088
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adaptin_N~Adaptin_N, Alpha_adaptinC2~Alpha_adaptinC2, Alpha_adaptinC2~B2-adapt-app_C
Common GO terms GO:0000139 - Golgi membrane
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
and 9 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 822
Hs

1 949
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ At
+ Hs
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024