HitPredict

Interactor 1: TLX2 (O43763)
T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein)
Gene: TLX2

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 284 Hs			1 2514
+	Hs
		212006 TLX3_HUMAN (6-273): 3.29e-41: 145: 57.55		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		679200 TLX1_HUMAN (79-283): 1.33e-38: 140: 62.62		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		213285 TLX2_HUMAN (1-284): 1.23e-51: 172: 100.00		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		211774 TLX3_HUMAN (6-273): 3.29e-41: 145: 57.55		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261413 TLX1_HUMAN (79-283): 1.33e-38: 140: 62.62		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		211992 TLX3_HUMAN (6-273): 3.29e-41: 145: 57.55		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		679188 TLX1_HUMAN (79-283): 1.33e-38: 140: 62.62		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		211987 TLX3_HUMAN (6-273): 3.29e-41: 145: 57.55		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		679183 TLX1_HUMAN (79-283): 1.33e-38: 140: 62.62		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Dm
		950002 UBX_DROME (23-218): 1.94e-31: 121: 19.05		RCOR_DROME (301-877): 2.05e-38: 156: 15.85
+	Hs
		213372 TLX2_HUMAN (1-284): 1.23e-51: 172: 100.00		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		213358 TLX2_HUMAN (1-284): 1.23e-51: 172: 100.00		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		211942 TLX3_HUMAN (6-273): 3.29e-41: 145: 57.55		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		679158 TLX1_HUMAN (79-283): 1.33e-38: 140: 62.62		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		211919 TLX3_HUMAN (6-273): 3.29e-41: 145: 57.55		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		679137 TLX1_HUMAN (79-283): 1.33e-38: 140: 62.62		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		595628 HXA5_HUMAN (37-232): 3.91e-32: 121: 22.77		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1300967 VSX1_HUMAN (14-260): 4.77e-30: 118: 20.00		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		882142 GSC_HUMAN (22-241): 1.47e-30: 116: 20.00		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		201848 HXA2_HUMAN (65-231): 5.39e-34: 128: 26.67		SYNJ1_HUMAN (1420-1892): 5.37e-09: 64.4: 11.18