HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 716
+	Hs
		1034848 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		IKKE_HUMAN (1-716): 1.32e-170: 508: 100.00
+	Hs
		684710 STIP1_HUMAN (85-258): 2.08e-19: 90.3: 24.08		IKKE_HUMAN (1-716): 1.32e-170: 508: 100.00
+	Hs
		685087 STIP1_HUMAN (85-258): 2.08e-19: 90.3: 24.08		TBK1_HUMAN (1-714): 4.2e-162: 486: 48.13
+	Dm
		1359353 Q9VH81_DROME (65-204): 3.01e-41: 151: 32.14		Q9V3Y8_DROME (1-682): 3.64e-128: 398: 35.60
+	Hs
		158449 FKBP4_HUMAN (15-264): 1.44e-37: 140: 15.85		IKKB_HUMAN (9-701): 6.33e-128: 399: 18.97
+	Hs
		158464 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		IKKB_HUMAN (9-701): 6.33e-128: 399: 18.97
+	Hs
		858688 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		MRCKB_HUMAN (7-705): 4e-115: 382: 17.25
+	Hs
		1123983 Q9BPW0_HUMAN (66-233): 1.14e-40: 149: 28.57		Q59GT1_HUMAN (9-686): 6.87e-117: 369: 18.72
+	Hs
		167503 TTC3_HUMAN (88-310): 3.46e-40: 151: 21.18		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Hs
		167633 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Hs
		167538 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Hs
		1123965 Q9BPW0_HUMAN (66-233): 1.14e-40: 149: 28.57		Q59GL9_HUMAN (61-520): 3.28e-112: 349: 22.57
+	Hs
		684793 STIP1_HUMAN (85-258): 2.08e-19: 90.3: 24.08		Q59GT1_HUMAN (9-686): 6.87e-117: 369: 18.72
+	Hs
		684792 STIP1_HUMAN (85-258): 2.08e-19: 90.3: 24.08		Q59GL9_HUMAN (61-520): 3.28e-112: 349: 22.57
+	Hs
		1034968 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		MARK4_HUMAN (9-262): 3.68e-86: 289: 28.21
+	Sc
		419790 STI1_YEAST (46-213): 5.97e-15: 77.1: 26.71		SNF1_YEAST (9-487): 5.7e-101: 325: 17.23
+	Hs
		858650 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		ULK2_HUMAN (1-221): 7.38e-24: 109: 31.28
+	Sc
		549703 STI1_YEAST (46-213): 5.97e-15: 77.1: 26.71		RAD53_YEAST (12-221): 8.31e-22: 102: 32.09