HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: SIM2 (Q14190)
Single-minded homolog 2 (Class E basic helix-loop-helix protein 15) (bHLHe15)
Gene: SIM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 667
+	Hs
		1050583 Q9BPW0_HUMAN (66-233): 1.14e-40: 149: 28.57		SIM2_HUMAN (1-667): 0: 541: 100.00
+	Hs
		1050593 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		SIM2_HUMAN (1-667): 0: 541: 100.00
+	Hs
		858623 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		SIM2_HUMAN (1-667): 0: 541: 100.00
+	Hs
		1034849 FKBP5_HUMAN (16-262): 7.6e-37: 138: 17.49		SIM2_HUMAN (1-667): 0: 541: 100.00
+	Hs
		684713 STIP1_HUMAN (85-258): 2.08e-19: 90.3: 24.08		SIM2_HUMAN (1-667): 0: 541: 100.00
+	Hs
		1306553 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		EPAS1_HUMAN (2-667): 1.56e-133: 415: 23.86
+	Hs
		1085720 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HIF1A_HUMAN (2-501): 2.75e-126: 395: 32.11
+	Hs
		126180 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		BMAL1_HUMAN (2-496): 1.25e-113: 356: 21.11
+	Hs
		181570 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		CLOCK_HUMAN (2-664): 9.36e-109: 350: 17.10
+	Hs
		1306179 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		NPAS1_HUMAN (2-494): 3.68e-101: 322: 31.60
+	Hs
		728969 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		AHR_HUMAN (5-518): 5.16e-91: 303: 20.04
+	Dm
		247725 Q9VH81_DROME (65-204): 3.01e-41: 151: 32.14		CLOCK_DROME (2-658): 2.36e-86: 293: 18.35
+	Dm
		247717 Q7KJA9_DROME (19-313): 4.17e-32: 128: 15.89		CLOCK_DROME (2-658): 2.36e-86: 293: 18.35