Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: GET4 (Q7L5D6)
Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35)
Gene: GET4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.683

The method score is based on:

Property Details
Experiments 34887561, 26186194, 35543156, 25036637
Identification Methods x-ray crystallography, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane
GO:0036503 - ERAD pathway
GO:0071816 - tail-anchored membrane protein insertion into ER membrane
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 313
Hs

1 327
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024