HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	35543156
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0060090 - molecular adaptor activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 540
+	Bt
		90459 E1B7G3_BOVIN (49-295): 4.31e-40: 149: 20.64		Q2KHZ7_BOVIN (1-539): 1.24e-48: 178: 49.63
+	Hs
		858646 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		195987 SGTB_HUMAN (1-311): 5.27e-54: 180: 57.24		PLXB1_HUMAN (78-332): 1.47e-10: 66.3: 19.62
+	Dm
		1197230 Q9VH81_DROME (65-204): 3.01e-41: 151: 32.14		Q86CW5_DROME (96-512): 1.1e-18: 92.2: 12.84
+	Dm
		375660 Q9VH81_DROME (65-204): 3.01e-41: 151: 32.14		RPB1_DROME (131-506): 1.34e-11: 69.8: 12.82
+	Mm
		88457 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		D3Z656_MOUSE (196-539): 1.13e-11: 69.8: 11.86
+	Dm
		375655 Q9V3E9_DROME (3-239): 1.24e-38: 144: 22.63		RPB1_DROME (131-506): 1.34e-11: 69.8: 12.82
+	Hs
		1300999 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Dm
		1366837 Q9VH81_DROME (65-204): 3.01e-41: 151: 32.14		Q9VPR2_DROME (35-406): 7.65e-09: 60.6: 11.02
+	Hs
		175005 OGT1_HUMAN (83-311): 1.42e-22: 100: 14.41		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		684846 STIP1_HUMAN (85-258): 2.08e-19: 90.3: 24.08		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Mm
		1186484 OGT1_MOUSE (83-311): 1.3e-22: 100: 14.41		HUWE1_MOUSE (108-539): 1.87e-18: 91.8: 13.89
+	Hs
		672833 CDC27_HUMAN (6-246): 2.49e-24: 105: 16.60		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		174891 OGT1_HUMAN (83-311): 1.42e-22: 100: 14.41		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		175053 OGT1_HUMAN (83-311): 1.42e-22: 100: 14.41		KMT2C_HUMAN (57-528): 6.72e-09: 61: 10.42
+	Hs
		684553 STIP1_HUMAN (85-258): 2.08e-19: 90.3: 24.08		SC24C_HUMAN (116-429): 9.64e-11: 66.7: 15.43