HitPredict

Interactor 1: MYO1B (O43795)
Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)
Gene: MYO1B

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1136 Hs			1 465
+	Hs
		227361 MYO7A_HUMAN (5-1132): 0: 1070: 29.06		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		1033097 MYO7A_HUMAN (5-1132): 0: 1070: 29.06		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	Hs
		1219401 MYO5A_HUMAN (2-1125): 0: 1013: 28.64		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	At
		98845 MYO17_ARATH (11-1078): 0: 1053: 29.55		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	Hs
		117883 MYO1F_HUMAN (16-716): 0: 617: 45.78		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		297276 MYO1D_HUMAN (16-794): 0: 706: 47.73		UBB_HUMAN (1-234): 1.14e-59: 197: 17.92
+	Hs
		226679 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226680 MYH10_HUMAN (771-1132): 7.68e-10: 65.8: 7.47		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226691 MYH11_HUMAN (701-1112): 2.54e-09: 63.9: 8.28		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		475417 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47