HitPredict

Interactor 1: MYO1B (O43795)
Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)
Gene: MYO1B

Interactor 2: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005769 - early endosome GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1136 Hs			1 173
+	Hs
		214543 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		260644 MYO5A_HUMAN (2-1125): 0: 1013: 28.64		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		260637 MYO5B_HUMAN (7-1125): 0: 995: 28.67		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		260504 MYO1D_HUMAN (16-794): 0: 706: 47.73		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		297327 MYO1D_HUMAN (16-794): 0: 706: 47.73		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		260550 MYO1E_HUMAN (16-729): 0: 622: 46.27		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Sp
		1350785 MYO1_SCHPO (3-718): 6.45e-176: 551: 40.90		FLP1_SCHPO (3-160): 6.58e-39: 140: 21.97
+	Hs
		117531 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		117646 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		117512 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		GAK_HUMAN (9-151): 1.05e-38: 141: 17.42
+	Hs
		260524 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		725123 MYH10_HUMAN (771-1132): 7.68e-10: 65.8: 7.47		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86