HitPredict

Interactor 1: MYO1B (O43795)
Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)
Gene: MYO1B

Interactor 2: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0045296 - cadherin binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1136 Hs			1 976
+	Hs
		214583 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		EPHA7_HUMAN (4-974): 0: 1128: 50.30
+	Hs
		214540 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		EPHA4_HUMAN (1-976): 0: 1121: 50.25
+	Hs
		214500 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		EPHA1_HUMAN (17-967): 0: 959: 49.38
+	Hs
		297302 MYO1D_HUMAN (16-794): 0: 706: 47.73		EPHA2_HUMAN (1-976): 0: 1141: 100.00
+	Hs
		297426 MYO1D_HUMAN (16-794): 0: 706: 47.73		EPHA6_HUMAN (9-973): 0: 1089: 47.51
+	Hs
		297294 MYO1D_HUMAN (16-794): 0: 706: 47.73		EPHA1_HUMAN (17-967): 0: 959: 49.38
+	Hs
		214488 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		INSRR_HUMAN (287-911): 2.3e-146: 470: 27.55
+	Hs
		214501 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		FGFR3_HUMAN (381-889): 9.01e-137: 431: 24.65
+	Zm
		41375 A0A1D6NKQ5_MAIZE (2-1078): 0: 1074: 30.73		B7ZZU3_MAIZE (331-896): 4.52e-164: 496: 17.29
+	Hs
		214472 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		LYN_HUMAN (607-879): 2.06e-64: 228: 42.91
+	Hs
		117602 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		EPHA2_HUMAN (1-976): 0: 1141: 100.00
+	Hs
		117721 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		EPHAA_HUMAN (3-975): 0: 942: 40.72
+	Hs
		665375 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		EPHA3_HUMAN (24-976): 0: 1111: 51.19
+	Hs
		297285 MYO1D_HUMAN (16-794): 0: 706: 47.73		INSRR_HUMAN (287-911): 2.3e-146: 470: 27.55
+	Hs
		297273 MYO1D_HUMAN (16-794): 0: 706: 47.73		LYN_HUMAN (607-879): 2.06e-64: 228: 42.91
+	Hs
		433732 MYO1E_HUMAN (16-729): 0: 622: 46.27		LYN_HUMAN (607-879): 2.06e-64: 228: 42.91
+	Hs
		433620 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		LYN_HUMAN (607-879): 2.06e-64: 228: 42.91