HitPredict

Interactor 1: MYO1B (O43795)
Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)
Gene: MYO1B

Interactor 2: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 30344098
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1136 Hs			1 323
+	Hs
		214546 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Mm
		906240 MYH6_MOUSE (1-1112): 0: 1033: 27.00		PP1A_MOUSE (1-323): 0: 579: 90.36
+	Hs
		906645 MYO5A_HUMAN (2-1125): 0: 1013: 28.64		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		906631 MYO5B_HUMAN (7-1125): 0: 995: 28.67		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Zm
		14346 A0A1D6G388_MAIZE (15-917): 0: 953: 32.30		B4FS28_MAIZE (9-303): 0: 546: 82.37
+	Hs
		297331 MYO1D_HUMAN (16-794): 0: 706: 47.73		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		737776 MYO1E_HUMAN (16-729): 0: 622: 46.27		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		906434 MYO1E_HUMAN (16-729): 0: 622: 46.27		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Dm
		819275 Q8IPH8_DROME (17-838): 8.78e-156: 514: 36.69		PP1B_DROME (1-323): 0: 552: 82.48
+	Dm
		1249916 Q9VLZ3_DROME (17-838): 1.01e-155: 513: 36.69		Q8T0U6_DROME (19-323): 0: 535: 83.39
+	Hs
		117617 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		117650 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		117651 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		724689 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		724746 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		528366 MYH6_HUMAN (735-1115): 3.32e-11: 70: 6.52		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		724747 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		724764 MYH9_HUMAN (694-1133): 5.37e-12: 72.7: 7.63		PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08
+	Hs
		725131 MYH10_HUMAN (771-1132): 7.68e-10: 65.8: 7.47		PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73