HitPredict

Interactor 1: CPSF5 (O43809)
Cleavage and polyadenylation specificity factor subunit 5 (Cleavage and polyadenylation specificity factor 25 kDa subunit) (CPSF 25 kDa subunit) (Cleavage factor Im complex 25 kDa subunit) (CFIm25) (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21) (Nudix hydrolase 21) (Pre-mRNA cleavage factor Im 68 kDa subunit)
Gene: NUDT21

Interactor 2: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16055720
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 227 Hs			1 1319
+	Hs
		214975 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		HUWE1_HUMAN (799-1317): 6.4e-169: 562: 35.32
+	Hs
		125027 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		WWP2_HUMAN (461-817): 1.56e-41: 167: 17.91
+	Hs
		215016 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		ITCH_HUMAN (468-799): 2.73e-28: 125: 19.42
+	Hs
		215043 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		SMUF1_HUMAN (539-719): 7.11e-18: 91.8: 16.82