HitPredict

Interactor 1: DUX1 (O43812)
Double homeobox protein 1
Gene: DUX1

Interactor 2: DUX3 (Q96PT4)
Putative double homeobox protein 3
Gene: DUX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 170 Hs			1 197
+	Hs
		1299575 DUX5_HUMAN (1-170): 9.85e-45: 147: 100.00		DUX3_HUMAN (1-197): 7.31e-45: 149: 100.00
+	Mm
		192290 PO3F4_MOUSE (5-162): 1.4e-32: 120: 17.72		ALX4_MOUSE (71-194): 2.65e-31: 119: 24.19
+	Hs
		201876 HXA3_HUMAN (39-169): 1.1e-32: 122: 23.24		ALX4_HUMAN (66-194): 1.05e-30: 117: 27.91
+	Hs
		590561 PO3F2_HUMAN (5-152): 4.46e-33: 123: 18.92		PO3F2_HUMAN (21-190): 3.72e-29: 113: 17.06
+	Rn
		914685 PO3F4_RAT (5-162): 1.4e-32: 120: 17.72		PO3F4_RAT (3-189): 2.31e-30: 115: 16.41
+	Hs
		540769 PO2F1_HUMAN (4-153): 1.25e-29: 115: 14.65		PO2F1_HUMAN (2-180): 3.27e-30: 118: 16.84
+	Dm
		557311 CF1A_DROME (5-169): 1.34e-31: 119: 16.97		UBX_DROME (59-182): 8.87e-30: 114: 20.31
+	Dm
		557307 CF1A_DROME (5-169): 1.34e-31: 119: 16.97		CF1A_DROME (8-195): 3.17e-29: 113: 16.93
+	Mm
		192275 ALX4_MOUSE (3-120): 1.73e-24: 99.6: 28.10		ALX4_MOUSE (71-194): 2.65e-31: 119: 24.19
+	Mm
		192296 ALX4_MOUSE (3-120): 1.73e-24: 99.6: 28.10		CDX4_MOUSE (1-193): 3.5e-29: 110: 17.01
+	Hs
		590563 PO3F2_HUMAN (5-152): 4.46e-33: 123: 18.92		PAX3_HUMAN (47-105): 1.37e-09: 58.6: 42.37
+	Hs
		540851 PO2F1_HUMAN (4-153): 1.25e-29: 115: 14.65		ZFHX3_HUMAN (52-191): 3.04e-11: 63.6: 17.73
+	Hs
		540785 PO2F1_HUMAN (4-153): 1.25e-29: 115: 14.65		PAX7_HUMAN (47-105): 3.22e-10: 60.5: 42.37
+	Hs
		197658 PO2F1_HUMAN (4-153): 1.25e-29: 115: 14.65		CRX_HUMAN (108-175): 5.62e-10: 59.3: 48.53
+	Dm
		985075 Q058W3_DROME (14-152): 4.59e-30: 114: 20.98		Q9W2P8_DROME (118-175): 1.79e-09: 58.2: 51.72
+	Mm
		192303 ALX4_MOUSE (3-120): 1.73e-24: 99.6: 28.10		Q8R0B5_MOUSE (26-122): 2.47e-11: 63.2: 29.90
+	Mm
		192304 ALX4_MOUSE (3-120): 1.73e-24: 99.6: 28.10		Q8VD35_MOUSE (47-122): 5.45e-11: 62: 35.53
+	Mm
		192281 ALX4_MOUSE (3-120): 1.73e-24: 99.6: 28.10		PAX3_MOUSE (47-105): 1.4e-09: 58.6: 42.37