HitPredict

Interactor 1: U3IP2 (O43818)
U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K)
Gene: RRP9

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 475 Hs			1 454
+	Hs
		346159 LIS1_HUMAN (187-474): 4.28e-75: 243: 16.77		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		348035 NLE1_HUMAN (23-350): 1.31e-68: 228: 16.53		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346404 WDR5_HUMAN (278-475): 3.08e-49: 173: 18.00		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346449 GBB2_HUMAN (215-475): 7.22e-48: 169: 14.39		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347517 FBXW7_HUMAN (269-474): 5.5e-38: 149: 15.24		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		215307 U3IP2_HUMAN (1-475): 7.27e-100: 309: 100.00		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Mm
		348444 FBXW7_MOUSE (269-474): 2.23e-38: 150: 15.24		MYC_MOUSE (1-454): 4.33e-119: 357: 89.01
+	Hs
		347550 SNR40_HUMAN (275-475): 8.06e-37: 140: 14.15		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		379200 WDR5_HUMAN (278-475): 3.08e-49: 173: 18.00		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379688 FBXW7_HUMAN (269-474): 5.5e-38: 149: 15.24		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379701 SNR40_HUMAN (275-475): 8.06e-37: 140: 14.15		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		607803 WDR5_HUMAN (278-475): 3.08e-49: 173: 18.00		USF1_HUMAN (175-453): 1.02e-39: 146: 18.40
+	Mm
		1112323 FBXW7_MOUSE (269-474): 2.23e-38: 150: 15.24		SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60
+	Hs
		903353 WDR5_HUMAN (278-475): 3.08e-49: 173: 18.00		MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71
+	Mm
		1257396 FBXW7_MOUSE (269-474): 2.23e-38: 150: 15.24		SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61
+	Hs
		738987 FBXW7_HUMAN (269-474): 5.5e-38: 149: 15.24		SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19
+	Mm
		659344 WDR5_MOUSE (278-475): 3.08e-49: 173: 18.00		MAX_MOUSE (354-454): 3.52e-25: 102: 32.67
+	Hs
		898091 WDR5_HUMAN (278-475): 3.08e-49: 173: 18.00		MAX_HUMAN (354-454): 1.39e-24: 101: 32.67
+	Hs
		1218698 SNR40_HUMAN (275-475): 8.06e-37: 140: 14.15		MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71
+	Hs
		898168 FBXW7_HUMAN (269-474): 5.5e-38: 149: 15.24		MAX_HUMAN (354-454): 1.39e-24: 101: 32.67