HitPredict

Interactor 1: AKAP8 (O43823)
A-kinase anchor protein 8 (AKAP-8) (A-kinase anchor protein 95 kDa) (AKAP 95)
Gene: AKAP8

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 692 Hs			1 768
+	Hs
		1042829 AKP8L_HUMAN (92-547): 1.22e-172: 510: 34.69		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041727 ZN326_HUMAN (127-549): 4.89e-140: 424: 28.70		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041276 AKP8L_HUMAN (92-547): 1.22e-172: 510: 34.69		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041499 AKP8L_HUMAN (92-547): 1.22e-172: 510: 34.69		CUL2_HUMAN (30-768): 0: 672: 26.17