Interactor 1: IDH3B (O43837)
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta)
Gene: IDH3B

Interactor 2: IDH3G (P51553)
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma)
Gene: IDH3G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Iso_dh~Iso_dh
Common GO terms GO:0000287 - magnesium ion binding
GO:0004449 - isocitrate dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006099 - tricarboxylic acid cycle
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 385
Hs

1 393
+ Hs
+ At
+ Hs
+ Hs
+ Dm
+ Ce
+ Ce
+ Sc
+ Sc
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024