HitPredict

Interactor 1: EDIL3 (O43854)
EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1)
Gene: EDIL3

Interactor 2: ITB5 (P18084)
Integrin beta-5
Gene: ITGB5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 799
+	Hs
		574530 MFGM_HUMAN (317-477): 2.21e-40: 151: 39.13		ITB5_HUMAN (1-799): 0: 786: 100.00
+	Hs
		574575 CNTP3_HUMAN (189-366): 2.03e-29: 124: 22.78		ITB5_HUMAN (1-799): 0: 786: 100.00
+	Mm
		82715 CNTP2_MOUSE (189-428): 1.04e-35: 143: 21.22		B9EJ72_MOUSE (557-741): 1.95e-27: 122: 17.80
+	Mm
		1112697 CNTP2_MOUSE (189-428): 1.04e-35: 143: 21.22		TEN4_MOUSE (557-727): 7.92e-24: 110: 18.08
+	Mm
		1321670 CNTP2_MOUSE (189-428): 1.04e-35: 143: 21.22		TEN1_MOUSE (593-740): 3.28e-15: 82.4: 11.35
+	Hs
		132255 NOTC2_HUMAN (12-163): 2.28e-10: 65.5: 19.19		DLL1_HUMAN (483-718): 1.51e-24: 111: 18.01
+	Hs
		132252 NOTC1_HUMAN (28-155): 5.02e-10: 64.3: 26.45		DLL1_HUMAN (483-718): 1.51e-24: 111: 18.01
+	Hs
		132268 NOTC3_HUMAN (28-155): 2.47e-09: 62: 28.39		DLL1_HUMAN (483-718): 1.51e-24: 111: 18.01
+	Dm
		90684 NOTCH_DROME (26-157): 3.49e-09: 61.6: 30.60		E1JHA6_DROME (346-553): 1.08e-16: 87.5: 13.92
+	Dm
		247192 Q9VU94_DROME (10-230): 1.36e-10: 66.3: 16.96		TENM_DROME (597-733): 3.98e-15: 82.4: 16.79
+	Dm
		246722 SERR_DROME (31-166): 1.64e-09: 62.4: 28.78		TENM_DROME (597-733): 3.98e-15: 82.4: 16.79