HitPredict

Interactor 1: SAHH2 (O43865)
S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2)
Gene: AHCYL1

Interactor 2: SAHH3 (Q96HN2)
Adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.13.2.1) (IP(3)Rs binding protein released with IP(3) 2) (IRBIT2) (Long-IRBIT) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2)
Gene: AHCYL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 28514442, 33961781, 34349018
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AdoHcyase~AdoHcyase, AdoHcyase~AdoHcyase_NAD, AdoHcyase_NAD~AdoHcyase_NAD
Common GO terms GO:0005829 - cytosol
GO:0006730 - one-carbon metabolic process
GO:0033353 - S-adenosylmethionine cycle
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 530
Hs

1 611
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Dm
+ Zm
+ Ph

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024