HitPredict

Interactor 1: CREB3 (O43889)
Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)]
Gene: CREB3

Interactor 2: AQP1 (P29972)
Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Urine water channel) (Water channel protein for red blood cells and kidney proximal tubule)
Gene: AQP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	21516116, 25910212
Identification Methods	two hybrid, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 371 Hs			1 269
+	Hs
		216700 CREB3_HUMAN (1-371): 1.33e-118: 350: 100.00		AQP4_HUMAN (9-266): 2.7e-91: 274: 43.46
+	Hs
		216684 CREB3_HUMAN (1-371): 1.33e-118: 350: 100.00		AQP2_HUMAN (4-267): 5.19e-88: 264: 43.94
+	Hs
		216699 CREB3_HUMAN (1-371): 1.33e-118: 350: 100.00		AQP5_HUMAN (1-267): 2.8e-82: 249: 45.52
+	Hs
		781295 CR3L1_HUMAN (23-327): 3.61e-45: 164: 27.17		AQP2_HUMAN (4-267): 5.19e-88: 264: 43.94