HitPredict

Interactor 1: CREB3 (O43889)
Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)]
Gene: CREB3

Interactor 2: CR3L3 (Q68CJ9)
Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3]
Gene: CREB3L3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 23661758, 20102225
Identification Methods fluorescent resonance energy transfer, peptide array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_1~bZIP_1
Common GO terms GO:0000139 - Golgi membrane
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 10 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 371
Hs

1 461
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Last updated: 15 Jul 2024