HitPredict

Interactor 1: CREB3 (O43889)
Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)]
Gene: CREB3

Interactor 2: RNF41 (Q9H4P4)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 371 Hs			1 317
+	Hs
		216715 CREB3_HUMAN (1-371): 1.33e-118: 350: 100.00		TRI26_HUMAN (3-301): 1.09e-51: 180: 12.62
+	Hs
		556779 CREB1_HUMAN (73-221): 8.07e-24: 102: 21.48		RO52_HUMAN (3-295): 1.95e-61: 204: 16.94
+	Hs
		556963 CREB1_HUMAN (73-221): 8.07e-24: 102: 21.48		TRIM5_HUMAN (11-298): 1.5e-56: 192: 19.19
+	Hs
		556944 CREB1_HUMAN (73-221): 8.07e-24: 102: 21.48		TRI11_HUMAN (3-295): 1.14e-56: 191: 13.92
+	Hs
		556914 CREB1_HUMAN (73-221): 8.07e-24: 102: 21.48		TRI22_HUMAN (3-300): 1.61e-53: 184: 17.21
+	Mm
		936268 CR3L3_MOUSE (27-290): 1.57e-44: 161: 35.06		TRAF6_MOUSE (2-132): 5.24e-30: 121: 34.85
+	Hs
		556856 CREB1_HUMAN (73-221): 8.07e-24: 102: 21.48		TRAF3_HUMAN (6-132): 1.42e-28: 117: 25.78
+	Mm
		964091 CREB1_MOUSE (73-221): 6.05e-24: 102: 21.48		TRAF3_MOUSE (6-132): 9.1e-28: 114: 24.62
+	At
		189255 HY5_ARATH (148-212): 4.35e-17: 79.9: 36.92		COP1_ARATH (9-211): 1.69e-31: 126: 20.69
+	At
		794472 Q1H5E5_ARATH (148-212): 4.35e-17: 79.9: 36.92		COP1_ARATH (9-211): 1.69e-31: 126: 20.69