HitPredict

Interactor 1: KIF1C (O43896)
Kinesin-like protein KIF1C
Gene: KIF1C

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	21988832, 30217970, 35271311, 36931259, 17979178, 19608861
Identification Methods	two hybrid, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005783 - endoplasmic reticulum
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1103 Hs			1 255
+	Hs
		231490 KIF1B_HUMAN (1-688): 7.01e-164: 531: 68.83		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910062 KI13B_HUMAN (1-829): 1.76e-142: 472: 34.92		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909583 KIF14_HUMAN (1-824): 6.41e-139: 460: 34.64		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Dm
		54781 A1ZA18_DROME (1-769): 2.13e-118: 405: 38.47		1433E_DROME (1-254): 2.95e-146: 411: 82.69
+	Mm
		702835 KIF5A_MOUSE (451-1078): 4.96e-19: 95.4: 10.55		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		909493 KIF5A_HUMAN (451-1078): 2.52e-17: 90: 9.53		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		702879 KINH_HUMAN (452-1055): 5.31e-15: 82.3: 9.00		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		910258 KINH_MOUSE (621-1007): 1.6e-12: 74.2: 8.66		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Mm
		910349 KI21B_MOUSE (599-1060): 1.25e-09: 64.9: 8.20		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00