Interactor 1: TYOBP (O43914)
TYRO protein tyrosine kinase-binding protein (DNAX-activation protein 12) (Killer-activating receptor-associated protein) (KAR-associated protein)
Gene: TYROBP

Interactor 2: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 9830044, 10940905
Identification Methods pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002283 - neutrophil activation involved in immune response
GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0032755 - positive regulation of interleukin-6 production
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 113
Hs

1 635
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024