HitPredict

Interactor 1: TYOBP (O43914)
TYRO protein tyrosine kinase-binding protein (DNAX-activation protein 12) (Killer-activating receptor-associated protein) (KAR-associated protein)
Gene: TYROBP

Interactor 2: CLM5 (Q6UXZ3)
CMRF35-like molecule 5 (CLM-5) (CD300 antigen-like family member D) (CMRF35-A4) (CD antigen CD300d)
Gene: CD300LD

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22291008
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 113 Hs			1 194
+	Hs
		66493 TYOBP_HUMAN (1-113): 8.75e-66: 195: 100.00		CLM7_HUMAN (17-192): 1.6e-61: 191: 44.32
+	Mm
		222481 TYOBP_MOUSE (1-113): 8.4e-64: 190: 73.04		CLM4_MOUSE (1-194): 2.3e-62: 194: 35.68
+	Hs
		3044 TYOBP_HUMAN (1-113): 8.75e-66: 195: 100.00		CD3CH_HUMAN (3-192): 1.85e-53: 171: 37.37
+	Hs
		217311 TYOBP_HUMAN (1-113): 8.75e-66: 195: 100.00		CLM6_HUMAN (2-194): 3.76e-52: 168: 40.39
+	Hs
		217362 TYOBP_HUMAN (1-113): 8.75e-66: 195: 100.00		TREM1_HUMAN (3-164): 2.57e-34: 122: 19.88
+	Hs
		217292 TYOBP_HUMAN (1-113): 8.75e-66: 195: 100.00		NCTR2_HUMAN (12-164): 3.34e-33: 121: 25.30
+	Mm
		222482 TYOBP_MOUSE (1-113): 8.4e-64: 190: 73.04		Q8BNV8_MOUSE (22-164): 2.77e-32: 117: 21.43
+	Hs
		217366 TYOBP_HUMAN (1-113): 8.75e-66: 195: 100.00		TREM2_HUMAN (7-169): 1.38e-27: 105: 21.47
+	Mm
		222485 TYOBP_MOUSE (1-113): 8.4e-64: 190: 73.04		TREM3_MOUSE (31-113): 3.87e-19: 82.5: 22.99
+	Hs
		122302 TYOBP_HUMAN (1-113): 8.75e-66: 195: 100.00		SIRB1_HUMAN (12-168): 1e-09: 58.6: 17.07