HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	20085707
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 586
+	Mm
		539749 AIRE_MOUSE (16-544): 2.93e-123: 374: 71.72		LMNB1_MOUSE (5-586): 2.21e-69: 236: 95.54
+	Hs
		359491 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82
+	Hs
		531571 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74
+	Hs
		359486 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82
+	Hs
		531559 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74
+	Hs
		821658 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		K2C6C_HUMAN (4-407): 3.4e-87: 283: 22.09
+	Hs
		380476 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85
+	Hs
		821652 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		K2C6C_HUMAN (4-407): 3.4e-87: 283: 22.09
+	Hs
		380468 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85
+	Hs
		595230 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Hs
		595372 UHRF1_HUMAN (268-410): 2.94e-28: 121: 23.87		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Hs
		595204 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Dr
		71460 Q1LYP4_DANRE (97-488): 3.91e-34: 140: 15.05		B3DKC5_DANRE (6-573): 3.64e-58: 207: 50.76
+	Hs
		359892 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		1059897 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		KRT84_HUMAN (60-390): 5.25e-59: 208: 20.24
+	Hs
		1059714 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		K2C73_HUMAN (2-391): 1.07e-53: 193: 19.70
+	Hs
		943630 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		KRT83_HUMAN (54-390): 2.93e-51: 185: 19.88
+	Hs
		1055184 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		K1H2_HUMAN (75-388): 3.56e-46: 170: 21.59
+	Hs
		443520 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		443482 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65