HitPredict

Interactor 1: O44490 (O44490)
ELKS/RAB6-interacting/CAST family member 2
Gene: elks-1

Interactor 2: MEK2 (Q10664)
Dual specificity mitogen-activated protein kinase kinase mek-2 (MAP kinase kinase mek-2) (EC 2.7.12.2)
Gene: mek-2

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	34416233, 35933017
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 836 Ce			1 387
+	Hs
		625176 MYH9_HUMAN (7-780): 4.82e-32: 137: 7.53		CDK2_HUMAN (70-366): 5.41e-127: 369: 23.43
+	Ce
		110169 O44490_CAEEL (1-836): 2.84e-48: 186: 100.00		GCK1_CAEEL (73-372): 6.07e-103: 319: 29.70
+	Hs
		681696 MYH9_HUMAN (7-780): 4.82e-32: 137: 7.53		AKT1_HUMAN (16-386): 3.77e-123: 366: 19.90
+	Hs
		960129 MYH13_HUMAN (7-788): 1.05e-31: 135: 10.57		CDK3_HUMAN (70-365): 2.21e-124: 362: 23.51
+	Ce
		219385 O44490_CAEEL (1-836): 2.84e-48: 186: 100.00		CST1_CAEEL (14-361): 4e-100: 307: 27.56
+	Hs
		528368 MYH6_HUMAN (17-777): 6.44e-30: 130: 8.61		CDK3_HUMAN (70-365): 2.21e-124: 362: 23.51
+	Hs
		502908 MYH3_HUMAN (285-836): 1.6e-24: 112: 11.73		CDK3_HUMAN (70-365): 2.21e-124: 362: 23.51
+	Hs
		522542 MYH1_HUMAN (6-650): 7.17e-23: 107: 8.58		CDK3_HUMAN (70-365): 2.21e-124: 362: 23.51
+	Hs
		1023138 MYH13_HUMAN (7-788): 1.05e-31: 135: 10.57		STK4_HUMAN (42-362): 8.59e-108: 326: 30.46
+	Hs
		522604 MYH7_HUMAN (9-589): 3.26e-19: 95.5: 7.99		CDK3_HUMAN (70-365): 2.21e-124: 362: 23.51
+	Hs
		1027453 MYH13_HUMAN (7-788): 1.05e-31: 135: 10.57		STK3_HUMAN (47-361): 1.83e-105: 321: 30.09
+	Hs
		528369 MYH6_HUMAN (17-777): 6.44e-30: 130: 8.61		STK4_HUMAN (42-362): 8.59e-108: 326: 30.46
+	Hs
		528371 MYH6_HUMAN (17-777): 6.44e-30: 130: 8.61		STK3_HUMAN (47-361): 1.83e-105: 321: 30.09
+	Hs
		502911 MYH3_HUMAN (285-836): 1.6e-24: 112: 11.73		STK4_HUMAN (42-362): 8.59e-108: 326: 30.46
+	Hs
		502912 MYH3_HUMAN (285-836): 1.6e-24: 112: 11.73		STK3_HUMAN (47-361): 1.83e-105: 321: 30.09
+	Hs
		522545 MYH1_HUMAN (6-650): 7.17e-23: 107: 8.58		STK4_HUMAN (42-362): 8.59e-108: 326: 30.46
+	Hs
		522546 MYH1_HUMAN (6-650): 7.17e-23: 107: 8.58		STK3_HUMAN (47-361): 1.83e-105: 321: 30.09
+	Hs
		522609 MYH7_HUMAN (9-589): 3.26e-19: 95.5: 7.99		STK4_HUMAN (42-362): 8.59e-108: 326: 30.46
+	Hs
		522610 MYH7_HUMAN (9-589): 3.26e-19: 95.5: 7.99		STK3_HUMAN (47-361): 1.83e-105: 321: 30.09
+	Hs
		528363 MYH6_HUMAN (17-777): 6.44e-30: 130: 8.61		MP2K3_HUMAN (58-377): 4.22e-55: 186: 34.55