Interactor 1: LTOR5 (O43504)
Ragulator complex protein LAMTOR5 (Hepatitis B virus X-interacting protein) (HBV X-interacting protein) (HBX-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5)
Gene: LAMTOR5

Interactor 2: LTOR4 (Q0VGL1)
Ragulator complex protein LAMTOR4 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4) [Cleaved into: Ragulator complex protein LAMTOR4, N-terminally processed]
Gene: LAMTOR4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.55 0.726

The method score is based on:

Property Details
Experiments 25416956, 32296183, 23414517, 33961781, 25561175, 40437099, 29123114, unassigned1304, 22980980, unassigned3799
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, validated two hybrid, x-ray crystallography, light scattering, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, mammalian protein protein interaction trap and 1 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0008361 - regulation of cell size
GO:0031902 - late endosome membrane
GO:0032008 - positive regulation of TOR signaling
and 6 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025