Interactor 1: O44501 (O44501)
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha)
Gene: fnta-1

Interactor 2: Q19752 (Q19752)
Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58)
Gene: fntb-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 19123269, 11731503
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PPTA~Prenyltrans
Common GO terms GO:0004660 - protein farnesyltransferase activity
GO:0005965 - protein farnesyltransferase complex
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 328
Ce

1 401
+ Hs
+ Rn
+ Dm
+ At
+ Ce
+ Hs
+ Rn
+ Sc
+ Hs
+ Sp
+ At
+ Rn
+ Sc
+ Dm
+ Hs
+ Sp
+ Dm
+ Sc

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Last updated: 15 Jul 2024