HitPredict

Interactor 1: BAG1 (O44739)
BAG family molecular chaperone regulator 1
Gene: bag-1

Interactor 2: HSP1 (P09446)
Heat shock protein hsp-1 (Heat shock 70 kDa protein A)
Gene: hsp-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.896

Property	Details
Experiments	22479492, 25053410, 31420580, 14704431
Identification Methods	pull down, two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051085 - chaperone cofactor-dependent protein refolding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 210 Ce			1 640
+	Hs
		714058 BAG1_HUMAN (17-193): 6.22e-65: 205: 27.68		HS71L_HUMAN (2-640): 0: 953: 80.60
+	Rn
		69526 BAG1_RAT (16-193): 1.4e-65: 207: 28.09		HSP7C_RAT (1-614): 0: 942: 86.32
+	Hs
		504647 BAG1_HUMAN (17-193): 6.22e-65: 205: 27.68		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Hs
		564166 BAG1_HUMAN (17-193): 6.22e-65: 205: 27.68		HSP76_HUMAN (2-640): 0: 942: 77.22
+	Mm
		571857 BAG1_MOUSE (16-193): 5.2e-65: 206: 27.53		HS71B_MOUSE (1-640): 0: 941: 80.09
+	Hs
		1120588 BAG1_HUMAN (17-193): 6.22e-65: 205: 27.68		Q53FC7_HUMAN (2-640): 0: 938: 76.60
+	Hs
		871754 BAG1_HUMAN (17-193): 6.22e-65: 205: 27.68		HSP72_HUMAN (2-640): 0: 925: 81.12