HitPredict

Interactor 1: O45189 (O45189)
RRM domain-containing protein
Gene: sup-12

Interactor 2: Q86G94 (Q86G94)
RRM domain-containing protein
Gene: asd-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.835

Property	Details
Experiments	25132178, 17923701, 14704431
Identification Methods	enzymatic study, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Ce			1 286
+	Ce
		107195 O45189_CAEEL (1-248): 1.23e-45: 154: 100.00		G5EEW7_CAEEL (1-286): 8.51e-62: 202: 100.00
+	Ce
		219932 O45189_CAEEL (1-248): 1.23e-45: 154: 100.00		FOX1_CAEEL (1-258): 1.83e-38: 141: 39.23
+	Hs
		198983 RBM38_HUMAN (8-234): 9.91e-39: 136: 43.04		RFOX2_HUMAN (1-84): 8.19e-32: 123: 50.00
+	Hs
		1314967 RBM24_HUMAN (26-231): 1.47e-34: 125: 44.66		RFOX1_HUMAN (1-85): 7.19e-32: 123: 48.24
+	Hs
		609861 ROA2_HUMAN (3-129): 2.56e-30: 117: 29.92		RBM39_HUMAN (1-182): 1.6e-32: 127: 19.05
+	Hs
		1054499 MSI2H_HUMAN (32-178): 3.13e-27: 108: 25.85		RBM39_HUMAN (1-182): 1.6e-32: 127: 19.05
+	Hs
		201670 MSI1H_HUMAN (32-205): 2.52e-26: 106: 22.16		RBM39_HUMAN (1-182): 1.6e-32: 127: 19.05
+	Hs
		198951 MSI2H_HUMAN (32-178): 3.13e-27: 108: 25.85		RFOX2_HUMAN (1-84): 8.19e-32: 123: 50.00
+	Hs
		62520 MSI1H_HUMAN (32-205): 2.52e-26: 106: 22.16		RFOX3_HUMAN (1-84): 2.69e-33: 125: 48.81
+	Hs
		1031328 PABP4_HUMAN (26-151): 1.68e-24: 103: 18.90		RBM39_HUMAN (1-182): 1.6e-32: 127: 19.05
+	Hs
		198809 MSI1H_HUMAN (32-205): 2.52e-26: 106: 22.16		RFOX2_HUMAN (1-84): 8.19e-32: 123: 50.00
+	Hs
		198832 ROA1_HUMAN (3-115): 1.04e-23: 99.8: 28.32		RFOX2_HUMAN (1-84): 8.19e-32: 123: 50.00
+	Hs
		453267 ROA1_HUMAN (3-115): 1.04e-23: 99.8: 28.32		TRA2B_HUMAN (1-77): 1.65e-29: 115: 35.00
+	Hs
		1031314 PABP4_HUMAN (26-151): 1.68e-24: 103: 18.90		TRA2A_HUMAN (1-77): 8.39e-28: 110: 28.75
+	Mm
		665755 RBM38_MOUSE (6-234): 2.99e-39: 137: 42.68		PABP1_MOUSE (2-64): 3.18e-14: 74.3: 30.16
+	Hs
		609811 ROA2_HUMAN (3-129): 2.56e-30: 117: 29.92		RBM3_HUMAN (2-60): 4.89e-18: 80.8: 32.79
+	Hs
		516358 ROA2_HUMAN (3-129): 2.56e-30: 117: 29.92		PABP1_HUMAN (2-64): 2.81e-14: 74.7: 30.16
+	Hs
		474021 PABP4_HUMAN (26-151): 1.68e-24: 103: 18.90		PAB4L_HUMAN (1-60): 3.27e-15: 76.5: 36.07
+	Hs
		516495 PABP4_HUMAN (26-151): 1.68e-24: 103: 18.90		PABP1_HUMAN (2-64): 2.81e-14: 74.7: 30.16
+	Hs
		453107 ROA1_HUMAN (3-115): 1.04e-23: 99.8: 28.32		PABP1_HUMAN (2-64): 2.81e-14: 74.7: 30.16