HitPredict

Interactor 1: O45550 (O45550)
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta)
Gene: dro-1

Interactor 2: Q20237 (Q20237)
Transcription factor CBF/NF-Y/archaeal histone domain-containing protein
Gene: drap-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CBFD_NFYB_HMF~CBFD_NFYB_HMF
Common GO terms	GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0017054 - negative cofactor 2 complex GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Ce			1 331
+	Ce
		220253 O45550_CAEEL (1-184): 1.25e-67: 206: 100.00		Q86G95_CAEEL (27-331): 1.59e-129: 373: 100.00
+	At
		1196509 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC3_ARATH (4-202): 2.4e-70: 219: 18.75
+	At
		1196497 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC9_ARATH (4-191): 3.22e-56: 184: 17.39
+	At
		1196501 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC6_ARATH (25-209): 5.51e-55: 180: 16.58
+	At
		1225881 NFYB8_ARATH (15-163): 1.59e-53: 169: 20.67		NFYC9_ARATH (4-191): 3.22e-56: 184: 17.39
+	At
		1123155 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYCA_ARATH (12-176): 8.7e-54: 176: 18.07
+	At
		1258009 NFYB8_ARATH (15-163): 1.59e-53: 169: 20.67		NFYC6_ARATH (25-209): 5.51e-55: 180: 16.58
+	At
		1123157 NFYB8_ARATH (15-163): 1.59e-53: 169: 20.67		NFYCA_ARATH (12-176): 8.7e-54: 176: 18.07
+	At
		1196508 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC1_ARATH (51-206): 1.49e-51: 172: 17.96
+	At
		1196498 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC2_ARATH (40-199): 9.79e-51: 168: 19.38
+	At
		1227610 NFYB8_ARATH (15-163): 1.59e-53: 169: 20.67		NFYC2_ARATH (40-199): 9.79e-51: 168: 19.38
+	At
		1196503 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC4_ARATH (51-206): 6.52e-48: 163: 14.94
+	At
		1258011 NFYB8_ARATH (15-163): 1.59e-53: 169: 20.67		NFYC4_ARATH (51-206): 6.52e-48: 163: 14.94
+	At
		1196502 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC7_ARATH (1-200): 9.65e-46: 156: 15.87
+	At
		1258010 NFYB8_ARATH (15-163): 1.59e-53: 169: 20.67		NFYC7_ARATH (1-200): 9.65e-46: 156: 15.87
+	At
		1117859 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC8_ARATH (41-209): 5.83e-44: 151: 15.91
+	At
		1117868 NFYB8_ARATH (15-163): 1.59e-53: 169: 20.67		NFYC8_ARATH (41-209): 5.83e-44: 151: 15.91
+	At
		1196500 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		NFYC5_ARATH (41-204): 1.12e-41: 144: 11.38
+	At
		1258008 NFYB8_ARATH (15-163): 1.59e-53: 169: 20.67		NFYC5_ARATH (41-204): 1.12e-41: 144: 11.38
+	At
		1196504 NFYB6_ARATH (15-166): 6.06e-54: 173: 19.38		DPB31_ARATH (31-153): 8.96e-34: 124: 20.33