HitPredict

Interactor 1: NHR49 (O45666)
Nuclear hormone receptor family member nhr-49
Gene: nhr-49

Interactor 2: MED15 (Q21955)
Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15)
Gene: mdt-15

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.681

Property	Details
Experiments	22511885, 16651656, 23791784, 20461074
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008340 - determination of adult lifespan GO:0019217 - regulation of fatty acid metabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 501 Ce			1 780
+	Ce
		220029 NHR4_CAEEL (2-438): 3.16e-96: 301: 22.89		MED15_CAEEL (1-780): 0: 1429: 100.00
+	Ce
		219827 NHR64_CAEEL (35-435): 2.53e-97: 300: 30.71		MED15_CAEEL (1-780): 0: 1429: 100.00
+	Ce
		785442 NHR10_CAEEL (19-421): 1.59e-95: 296: 28.01		MED15_CAEEL (1-780): 0: 1429: 100.00
+	Ce
		106976 NH114_CAEEL (21-426): 1.22e-93: 292: 24.16		MED15_CAEEL (1-780): 0: 1429: 100.00
+	Ce
		954782 NHR69_CAEEL (31-451): 2.25e-93: 290: 31.24		MED15_CAEEL (1-780): 0: 1429: 100.00
+	Ce
		1089231 NHR28_CAEEL (33-478): 6.32e-90: 283: 20.56		MED15_CAEEL (1-780): 0: 1429: 100.00
+	Ce
		1094533 Q86PI8_CAEEL (35-113): 6.47e-29: 117: 59.49		MED15_CAEEL (1-780): 0: 1429: 100.00
+	Ce
		1094536 Q95QT4_CAEEL (35-417): 6.32e-26: 111: 24.82		MED15_CAEEL (1-780): 0: 1429: 100.00