HitPredict

Interactor 1: NHR49 (O45666)
Nuclear hormone receptor family member nhr-49
Gene: nhr-49

Interactor 2: Q9XXK5 (Q9XXK5)
Suppressor of Constitutive Dauer formation
Gene: scd-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.559

Property	Details
Experiments	22511885, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 501 Ce			1 947
+	Hs
		369789 ESR1_HUMAN (14-467): 1.59e-96: 305: 19.87		MRCKA_HUMAN (25-573): 4.28e-57: 217: 15.21
+	Hs
		309272 ESR1_HUMAN (14-467): 1.59e-96: 305: 19.87		KIF4A_HUMAN (44-529): 1.4e-27: 122: 11.85
+	Hs
		370586 ESR1_HUMAN (14-467): 1.59e-96: 305: 19.87		ITSN2_HUMAN (136-533): 8.57e-21: 100: 10.36
+	Hs
		587127 RXRA_HUMAN (1-423): 1.18e-104: 322: 27.66		MYH9_HUMAN (77-495): 1.69e-10: 67.6: 13.22
+	Hs
		659748 RXRB_HUMAN (33-423): 4.66e-102: 318: 28.65		MRCKB_HUMAN (222-529): 1.9e-11: 70.4: 8.33
+	Hs
		369641 ESR1_HUMAN (14-467): 1.59e-96: 305: 19.87		PLEC_HUMAN (11-524): 4.78e-15: 82.4: 12.76
+	Hs
		370819 ESR1_HUMAN (14-467): 1.59e-96: 305: 19.87		MRCKB_HUMAN (222-529): 1.9e-11: 70.4: 8.33
+	Hs
		369096 ESR1_HUMAN (14-467): 1.59e-96: 305: 19.87		MYH9_HUMAN (77-495): 1.69e-10: 67.6: 13.22
+	Hs
		370120 ESR1_HUMAN (14-467): 1.59e-96: 305: 19.87		MY18A_HUMAN (87-541): 2.33e-09: 63.9: 7.87
+	Hs
		490079 NR2F6_HUMAN (11-430): 3.42e-90: 283: 23.90		BAZ2B_HUMAN (30-288): 8.45e-13: 75: 14.56
+	Mm
		740808 THB_MOUSE (7-421): 5.33e-89: 282: 19.38		PLEC_MOUSE (13-362): 3.5e-09: 63.1: 11.71