HitPredict

Interactor 1: CTBP (O46036)
C-terminal-binding protein (CtBP protein) (dCtBP)
Gene: CTBP

Interactor 2: KNRL (P13054)
Knirps-related protein (Nuclear receptor subfamily 0 group A member 2)
Gene: KNRL

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 476 Dm			1 647
+	Dm
		220623 CTBP_DROME (1-476): 0: 574: 100.00		TLL_DROME (13-227): 1.38e-49: 181: 21.94
+	Dm
		220639 CTBP_DROME (1-476): 0: 574: 100.00		HR78_DROME (12-153): 1.16e-44: 170: 32.64
+	Dm
		220616 CTBP_DROME (1-476): 0: 574: 100.00		KNIR_DROME (10-143): 1.02e-45: 169: 69.12
+	Dm
		220621 CTBP_DROME (1-476): 0: 574: 100.00		EGON_DROME (10-104): 9.26e-45: 165: 87.37
+	Hs
		823771 CTBP2_HUMAN (14-457): 1.42e-166: 478: 62.02		NR2C2_HUMAN (12-307): 3.12e-71: 243: 22.93
+	Hs
		823968 CTBP1_HUMAN (1-456): 3.08e-165: 475: 60.31		NR2C2_HUMAN (12-307): 3.12e-71: 243: 22.93
+	Hs
		369269 CTBP2_HUMAN (14-457): 1.42e-166: 478: 62.02		ESR1_HUMAN (6-228): 3.32e-50: 185: 23.77
+	Hs
		369538 CTBP1_HUMAN (1-456): 3.08e-165: 475: 60.31		ESR1_HUMAN (6-228): 3.32e-50: 185: 23.77
+	Hs
		197175 SERA_HUMAN (28-439): 8.78e-136: 403: 25.48		ESR1_HUMAN (6-228): 3.32e-50: 185: 23.77
+	Hs
		197178 SERA_HUMAN (28-439): 8.78e-136: 403: 25.48		GCR_HUMAN (6-196): 1.36e-46: 178: 21.99
+	Hs
		881244 CTBP2_HUMAN (14-457): 1.42e-166: 478: 62.02		ESR2_HUMAN (14-89): 3.44e-15: 80.9: 47.37
+	Hs
		1032535 CTBP1_HUMAN (1-456): 3.08e-165: 475: 60.31		ESR2_HUMAN (14-89): 3.44e-15: 80.9: 47.37