HitPredict

Interactor 1: SKP2B (O49286)
F-box protein SKP2B (F-box/LRR-repeat protein 5) (AtFB5) (SKP2-like protein 2) (AtSKP2;2)
Gene: SKP2B

Interactor 2: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12468727
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019005 - SCF ubiquitin ligase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 360 At			1 738
+	At
		1277334 SKP2A_ARATH (1-360): 1.62e-80: 251: 83.06		CUL1_ARATH (1-738): 0: 837: 100.00
+	Hs
		1042879 KDM2A_HUMAN (34-269): 8.94e-43: 160: 18.65		CUL3_HUMAN (1-738): 0: 796: 30.09
+	Hs
		1031192 SKP2_HUMAN (17-316): 2.92e-45: 162: 23.22		CUL4A_HUMAN (13-738): 0: 788: 34.61
+	At
		1277345 EBF1_ARATH (87-280): 3.08e-22: 99.8: 29.08		CUL1_ARATH (1-738): 0: 837: 100.00
+	At
		1123013 TIR1_ARATH (1-356): 8.8e-19: 89.7: 16.99		CUL1_ARATH (1-738): 0: 837: 100.00
+	At
		1277335 AFB3_ARATH (63-320): 7.64e-18: 86.7: 18.91		CUL1_ARATH (1-738): 0: 837: 100.00
+	Hs
		1041256 FBXL7_HUMAN (14-359): 7.87e-56: 191: 17.96		CUL1_HUMAN (4-738): 0: 729: 30.41
+	Hs
		1043217 FXL15_HUMAN (124-331): 2.09e-30: 119: 26.55		CUL4A_HUMAN (13-738): 0: 788: 34.61
+	Hs
		1041267 FBXL2_HUMAN (30-344): 3.36e-47: 167: 24.71		CUL1_HUMAN (4-738): 0: 729: 30.41
+	Hs
		1041552 SCRIB_HUMAN (6-269): 2.5e-21: 97.8: 12.13		CUL3_HUMAN (1-738): 0: 796: 30.09
+	Hs
		1031190 SKP2_HUMAN (17-316): 2.92e-45: 162: 23.22		CUL1_HUMAN (4-738): 0: 729: 30.41
+	Hs
		1041100 KDM2B_HUMAN (33-269): 5.68e-43: 161: 17.65		CUL1_HUMAN (4-738): 0: 729: 30.41
+	Mm
		1376707 SKP2_MOUSE (17-331): 6.19e-44: 158: 21.89		CUL1_MOUSE (4-738): 0: 729: 30.41
+	Hs
		1041088 FXL14_HUMAN (26-356): 2.23e-41: 151: 21.27		CUL1_HUMAN (4-738): 0: 729: 30.41
+	Hs
		1041495 FBXL2_HUMAN (30-344): 3.36e-47: 167: 24.71		CUL2_HUMAN (1-738): 0: 688: 27.05
+	Hs
		1041146 FXL20_HUMAN (40-322): 1.09e-31: 125: 26.22		CUL1_HUMAN (4-738): 0: 729: 30.41
+	Mm
		1321914 FXL20_MOUSE (40-322): 1.12e-31: 125: 26.22		CUL1_MOUSE (4-738): 0: 729: 30.41
+	Hs
		1031191 SKP2_HUMAN (17-316): 2.92e-45: 162: 23.22		CUL2_HUMAN (1-738): 0: 688: 27.05
+	Hs
		1041197 FXL15_HUMAN (124-331): 2.09e-30: 119: 26.55		CUL1_HUMAN (4-738): 0: 729: 30.41
+	Hs
		1031247 SKP2_HUMAN (17-316): 2.92e-45: 162: 23.22		CUL5_HUMAN (3-738): 0: 615: 24.14