HitPredict

Interactor 1: DDB1B (O49552)
DNA damage-binding protein 1b (UV-damaged DNA-binding protein 1b) (DDB1b)
Gene: DDB1B

Interactor 2: SPA1 (Q9SYX2)
Protein SUPPRESSOR OF PHYA-105 1 (EC 2.7.-.-)
Gene: SPA1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.806

Property	Details
Experiments	20061554, 24067658
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005634 - nucleus GO:0009585 - red, far-red light phototransduction
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1088 At			1 1029
+	At
		1340745 DDB1A_ARATH (1-1088): 0: 1312: 91.27		SPA1_ARATH (1-1029): 0: 809: 100.00
+	At
		221836 DDB1B_ARATH (1-1088): 0: 1316: 100.00		SPA2_ARATH (4-1029): 0: 655: 39.44
+	At
		1340747 DDB1A_ARATH (1-1088): 0: 1312: 91.27		SPA2_ARATH (4-1029): 0: 655: 39.44
+	At
		221830 DDB1B_ARATH (1-1088): 0: 1316: 100.00		SPA4_ARATH (246-1029): 3.77e-136: 431: 37.35
+	At
		221832 DDB1B_ARATH (1-1088): 0: 1316: 100.00		SPA3_ARATH (240-1029): 1.1e-135: 431: 36.17
+	At
		1277622 DDB1A_ARATH (1-1088): 0: 1312: 91.27		SPA4_ARATH (246-1029): 3.77e-136: 431: 37.35
+	At
		1338320 DDB1A_ARATH (1-1088): 0: 1312: 91.27		SPA3_ARATH (240-1029): 1.1e-135: 431: 36.17
+	Hs
		1082292 DDB1_HUMAN (3-1088): 0: 1202: 51.13		COP1_HUMAN (487-1029): 3.32e-87: 298: 36.07
+	At
		221820 DDB1B_ARATH (1-1088): 0: 1316: 100.00		COP1_ARATH (807-1028): 1.83e-29: 127: 15.81
+	At
		794497 DDB1A_ARATH (1-1088): 0: 1312: 91.27		COP1_ARATH (807-1028): 1.83e-29: 127: 15.81
+	Hs
		903254 DDB1_HUMAN (3-1088): 0: 1202: 51.13		WDR5_HUMAN (605-920): 2.06e-65: 225: 18.71
+	Hs
		1082374 DDB1_HUMAN (3-1088): 0: 1202: 51.13		TBL1R_HUMAN (745-1027): 8.36e-60: 215: 13.47
+	Hs
		1082263 DDB1_HUMAN (3-1088): 0: 1202: 51.13		WDR5B_HUMAN (545-836): 4.25e-42: 159: 13.71
+	Hs
		1082327 DDB1_HUMAN (3-1088): 0: 1202: 51.13		SNR40_HUMAN (922-1027): 1.25e-17: 87.6: 9.43
+	Hs
		1073168 SF3B3_HUMAN (3-1085): 0: 1013: 21.29		NLE1_HUMAN (877-1027): 1.15e-34: 141: 15.29
+	Hs
		253256 CPSF1_HUMAN (3-519): 7.47e-118: 398: 17.30		KI21B_HUMAN (8-922): 7.02e-53: 204: 9.42
+	Hs
		1014208 CPSF1_HUMAN (3-519): 7.47e-118: 398: 17.30		NLE1_HUMAN (877-1027): 1.15e-34: 141: 15.29