HitPredict

Interactor 1: CCR6 (O54689)
C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (KY411) (CD antigen CD196)
Gene: CCR6

Interactor 2: CCL20 (O89093)
C-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (CC chemokine ST38) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20)
Gene: CCL20

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9862452
Identification Methods	fluorescence technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006935 - chemotaxis GO:0060326 - cell chemotaxis GO:0072678 - T cell migration GO:0072679 - thymocyte migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 367 Mm			1 97
+	Hs
		945622 ACKR4_HUMAN (2-335): 1.7e-87: 269: 36.72		CCL8_HUMAN (16-97): 7.43e-29: 101: 28.05
+	Hs
		945630 ACKR4_HUMAN (2-335): 1.7e-87: 269: 36.72		CCL7_HUMAN (16-96): 6.49e-28: 98.9: 25.93
+	Hs
		1305163 ACKR4_HUMAN (2-335): 1.7e-87: 269: 36.72		CCL13_HUMAN (9-97): 3.51e-27: 97: 23.60
+	Hs
		528225 ACKR4_HUMAN (2-335): 1.7e-87: 269: 36.72		CCL2_HUMAN (16-96): 4.52e-26: 94.3: 23.46
+	Hs
		849662 CCR6_HUMAN (1-367): 4.89e-84: 261: 74.60		CCL20_HUMAN (3-97): 4.48e-28: 99.3: 64.21
+	Hs
		526561 CXCR5_HUMAN (11-366): 1.33e-82: 257: 32.14		CCL4_HUMAN (3-93): 7.2e-30: 103: 29.67
+	Hs
		179471 ACKR4_HUMAN (2-335): 1.7e-87: 269: 36.72		CCL25_HUMAN (8-95): 1.34e-22: 87: 30.44
+	Hs
		486231 CXCR5_HUMAN (11-366): 1.33e-82: 257: 32.14		CCL3_HUMAN (1-94): 5.26e-28: 98.9: 27.66
+	Hs
		1306053 ACKR4_HUMAN (2-335): 1.7e-87: 269: 36.72		CCL19_HUMAN (17-97): 1.07e-21: 83.2: 28.40
+	Hs
		134312 ACKR4_HUMAN (2-335): 1.7e-87: 269: 36.72		CCL21_HUMAN (24-93): 5.24e-21: 82.4: 33.33
+	Hs
		849723 CCR8_HUMAN (16-356): 4.2e-82: 255: 32.27		CCL18_HUMAN (6-94): 3.99e-26: 93.9: 31.11
+	Mm
		534669 CCR3_MOUSE (1-353): 3.23e-80: 251: 33.43		CCL4_MOUSE (16-93): 5.22e-26: 93.9: 21.80
+	Mm
		500591 CCR3_MOUSE (1-353): 3.23e-80: 251: 33.43		CCL3_MOUSE (1-94): 7.49e-26: 93.6: 25.26
+	Hs
		607528 CCR8_HUMAN (16-356): 4.2e-82: 255: 32.27		CCL1_HUMAN (1-90): 1.56e-23: 87.8: 26.67
+	Hs
		528245 CXCR5_HUMAN (11-366): 1.33e-82: 257: 32.14		CCL5_HUMAN (14-93): 5.12e-22: 83.5: 27.50
+	Hs
		849725 CCR8_HUMAN (16-356): 4.2e-82: 255: 32.27		CCL17_HUMAN (1-91): 6.06e-22: 83.5: 28.57
+	Hs
		180159 CXCR5_HUMAN (11-366): 1.33e-82: 257: 32.14		CCL16_HUMAN (27-89): 1.55e-20: 80.8: 33.33
+	Hs
		180162 CCR8_HUMAN (16-356): 4.2e-82: 255: 32.27		CCL16_HUMAN (27-89): 1.55e-20: 80.8: 33.33
+	Hs
		802290 XCR1_HUMAN (9-340): 1.61e-80: 251: 26.51		XCL1_HUMAN (7-96): 6.42e-22: 83.9: 27.96
+	Hs
		180158 CCR1_HUMAN (24-353): 1.01e-78: 247: 33.33		CCL16_HUMAN (27-89): 1.55e-20: 80.8: 33.33