Interactor 1: PIAS3 (O54714)
E3 SUMO-protein ligase PIAS3 (EC 2.3.2.-) (E3 SUMO-protein transferase PIAS3) (Protein inhibitor of activated STAT protein 3)
Gene: PIAS3

Interactor 2: IRF1 (P15314)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.573

The method score is based on:

Property Details
Experiments 12387893
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 628
Mm

1 329
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024