Interactor 1: DFFA (O54786)
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD)
Gene: DFFA

Interactor 2: DFFB (O54788)
DNA fragmentation factor subunit beta (EC 3.-.-.-) (Caspase-activated deoxyribonuclease) (CAD) (Caspase-activated DNase) (DNA fragmentation factor 40 kDa subunit) (DFF-40)
Gene: DFFB

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.888

The method score is based on:

Property Details
Experiments 15572351, 9422506, 22727028, 10932250
Identification Methods pull down, peptide array, nuclear magnetic resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CIDE-N~CIDE-N
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006309 - apoptotic DNA fragmentation
GO:1902511 - negative regulation of apoptotic DNA fragmentation
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 331
Mm

1 344
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024