HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 18840695, 17353363
Identification Methods anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005080 - protein kinase C binding
GO:0005178 - integrin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005925 - focal adhesion
and 13 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 787
Mm

1 535
+ Hs
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024