HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: ITAV (P43406)
Integrin alpha-V (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]
Gene: Itgav

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 17485491
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_2~Integrin_alpha2, I-EGF_1~Integrin_alpha2, Integrin_alpha~Integrin_b_cyt, Integrin_B_tail~Integrin_alpha2, FG-GAP~Integrin_beta, Integrin_alpha2~Integrin_beta, Integrin_alpha2~PSI_integrin
Common GO terms GO:0001968 - fibronectin binding
GO:0002020 - protease binding
GO:0005178 - integrin binding
GO:0005925 - focal adhesion
GO:0007160 - cell-matrix adhesion
and 30 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 787
Mm

1 1044
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024