HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: PLEC (Q9QXS1)
Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6)
Gene: PLEC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30333137
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion GO:0016324 - apical plasma membrane GO:0071260 - cellular response to mechanical stimulus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 787 Mm			1 4691
+	Mm
		447132 ITB1_MOUSE (10-786): 0: 733: 43.27		PLEC_MOUSE (1-4691): 0: 1786: 100.00
+	Mm
		515690 ITB2_MOUSE (24-785): 0: 625: 38.45		PLEC_MOUSE (1-4691): 0: 1786: 100.00
+	Hs
		556444 ITB4_HUMAN (5-717): 0: 615: 34.35		PLEC_HUMAN (1-4691): 0: 1743: 93.40
+	Hs
		403752 ITB1_HUMAN (10-786): 0: 728: 43.52		ACTN1_HUMAN (163-895): 3.91e-109: 375: 24.48
+	Gg
		396530 ITB1_CHICK (8-786): 0: 729: 43.23		ACTN1_CHICK (160-895): 4.81e-107: 368: 24.51
+	Mm
		222535 ITB3_MOUSE (1-787): 0: 793: 100.00		SPTB2_MOUSE (1398-3172): 3.34e-19: 98.9: 10.58
+	Mm
		515654 ITB2_MOUSE (24-785): 0: 625: 38.45		SPTB2_MOUSE (1398-3172): 3.34e-19: 98.9: 10.58
+	Hs
		556435 ITB4_HUMAN (5-717): 0: 615: 34.35		DYST_HUMAN (4193-4603): 9.26e-20: 101: 19.22
+	Dm
		246721 TENM_DROME (624-726): 1.3e-15: 84: 15.60		ACTN_DROME (183-902): 3.2e-119: 405: 23.46
+	Hs
		1356681 TEN1_HUMAN (355-501): 1.87e-09: 63.6: 9.52		MACF1_HUMAN (4281-4623): 2.12e-35: 152: 18.95
+	Dm
		54279 TENM_DROME (624-726): 1.3e-15: 84: 15.60		A1Z9J0_DROME (457-1880): 6.8e-18: 94.7: 9.54
+	Dm
		54284 TENM_DROME (624-726): 1.3e-15: 84: 15.60		A1Z9J1_DROME (471-1132): 1.73e-09: 66.9: 10.74
+	Dm
		54273 NOTCH_DROME (353-625): 9.57e-14: 77.8: 11.96		A1Z9I9_DROME (471-1146): 3.51e-09: 65.8: 9.84