Interactor 1: LAT (O54957)
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)
Gene: LAT

Interactor 2: PLCG1 (Q62077)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 24584089, 22561606, 21487392
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, cross-linking study
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0008180 - COP9 signalosome
GO:0019722 - calcium-mediated signaling
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 242
Mm

1 1302
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024