HitPredict

Interactor 1: LAT (O54957)
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)
Gene: LAT

Interactor 2: THMS1 (Q8BGW0)
Protein THEMIS (Grb2-associating protein) (Gasp) (Protein thylex) (Thymocyte-expressed molecule involved in selection)
Gene: Themis

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.552

The method score is based on:

Property Details
Experiments 24584089, 22561606
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002250 - adaptive immune response
GO:0005911 - cell-cell junction
GO:0008180 - COP9 signalosome
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 242
Mm

1 636
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024