HitPredict

Interactor 1: ACK1 (O54967)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2)
Gene: Tnk2

Interactor 2: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.812

Property	Details
Experiments	17182860, 28190767
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH3_9~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1055 Mm			1 734
+	Hs
		475664 ACK1_HUMAN (1-1055): 0: 831: 92.89		UBC_HUMAN (77-724): 0: 790: 97.22
+	Rn
		1144043 FYN_RAT (1-400): 6.61e-129: 404: 30.94		UBC_RAT (1-724): 0: 898: 97.51
+	Rn
		1144206 FGR_RAT (1-401): 1.46e-128: 402: 30.85		UBC_RAT (1-724): 0: 898: 97.51
+	Hs
		337319 ABL1_HUMAN (2-994): 5.34e-148: 472: 20.16		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		411563 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		475292 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		475716 TNK1_HUMAN (1-517): 7.11e-120: 384: 40.41		UBC_HUMAN (77-724): 0: 790: 97.22
+	Rn
		1144295 Q9QX70_RAT (105-387): 4.43e-52: 201: 38.87		UBC_RAT (1-724): 0: 898: 97.51
+	Rn
		989765 LYN_RAT (121-385): 1.96e-51: 191: 40.08		UBC_RAT (1-724): 0: 898: 97.51
+	Hs
		337826 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		397932 ACK1_HUMAN (1-1055): 0: 831: 92.89		ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69
+	Hs
		337825 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70