HitPredict

Interactor 1: ACK1 (O54967)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2)
Gene: Tnk2

Interactor 2: CAD10 (P70408)
Cadherin-10 (T2-cadherin)
Gene: Cdh10

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29254152
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005912 - adherens junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1055 Mm			1 788
+	Hs
		521882 FAK1_HUMAN (6-718): 6.3e-131: 425: 21.35		CADH1_HUMAN (3-785): 0: 629: 33.71
+	Hs
		433230 YES_HUMAN (1-400): 5.47e-131: 410: 30.18		CADH1_HUMAN (3-785): 0: 629: 33.71
+	Hs
		411968 FYN_HUMAN (1-400): 2.25e-129: 405: 30.94		CADH1_HUMAN (3-785): 0: 629: 33.71
+	Hs
		433353 YES_HUMAN (1-400): 5.47e-131: 410: 30.18		DSC3_HUMAN (23-777): 0: 619: 27.76
+	Hs
		521694 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		CADH1_HUMAN (3-785): 0: 629: 33.71
+	Hs
		337849 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		CADH1_HUMAN (3-785): 0: 629: 33.71
+	Hs
		337573 ABL1_HUMAN (2-994): 5.34e-148: 472: 20.16		CELR3_HUMAN (267-776): 6.24e-104: 354: 18.43
+	Hs
		412380 FYN_HUMAN (1-400): 2.25e-129: 405: 30.94		CELR3_HUMAN (267-776): 6.24e-104: 354: 18.43
+	Hs
		702755 FAK1_HUMAN (6-718): 6.3e-131: 425: 21.35		CADH5_HUMAN (2-513): 2.5e-92: 308: 23.31
+	Hs
		522815 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		CADH5_HUMAN (2-513): 2.5e-92: 308: 23.31
+	Hs
		523158 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		CELR2_HUMAN (377-768): 1.86e-85: 299: 18.80
+	Hs
		433517 YES_HUMAN (1-400): 5.47e-131: 410: 30.18		PCDB3_HUMAN (315-771): 3.65e-69: 245: 17.56
+	Hs
		580213 EPHA4_HUMAN (74-487): 1.22e-123: 404: 24.82		CADH2_HUMAN (2-479): 4.04e-70: 249: 21.02
+	Hs
		872632 EPHA4_HUMAN (74-487): 1.22e-123: 404: 24.82		DSC2_HUMAN (4-484): 1.11e-55: 208: 21.00
+	Hs
		411680 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		DSC2_HUMAN (4-484): 1.11e-55: 208: 21.00
+	Hs
		433707 LYN_HUMAN (85-387): 1.5e-107: 347: 36.07		DSC2_HUMAN (4-484): 1.11e-55: 208: 21.00
+	Hs
		338014 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		CADH5_HUMAN (2-513): 2.5e-92: 308: 23.31
+	Hs
		337911 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		CADH2_HUMAN (2-479): 4.04e-70: 249: 21.02
+	Hs
		339196 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		PCDB3_HUMAN (315-771): 3.65e-69: 245: 17.56
+	Hs
		338302 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		DSC2_HUMAN (4-484): 1.11e-55: 208: 21.00