HitPredict

Interactor 1: ACK1 (O54967)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2)
Gene: Tnk2

Interactor 2: RHG23 (Q69ZH9)
Rho GTPase-activating protein 23 (Rho-type GTPase-activating protein 23)
Gene: Arhgap23

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29254152
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1055 Mm			1 1483
+	Mm
		222876 ACK1_MOUSE (1-1055): 0: 865: 100.00		SRGP2_MOUSE (772-1477): 3.22e-86: 307: 16.85
+	Mm
		222853 ACK1_MOUSE (1-1055): 0: 865: 100.00		RHG21_MOUSE (23-887): 6.78e-66: 249: 23.30
+	Hs
		337325 ABL1_HUMAN (2-994): 5.34e-148: 472: 20.16		BCR_HUMAN (174-1073): 5.91e-94: 334: 17.32
+	Hs
		337453 ABL1_HUMAN (2-994): 5.34e-148: 472: 20.16		ABR_HUMAN (322-1095): 1.22e-79: 284: 15.18
+	Hs
		337492 ABL1_HUMAN (2-994): 5.34e-148: 472: 20.16		RHG17_HUMAN (780-1445): 4.76e-78: 280: 15.48
+	Hs
		442768 HCK_HUMAN (1-397): 5.42e-125: 393: 29.90		BCR_HUMAN (174-1073): 5.91e-94: 334: 17.32
+	Hs
		412284 FYN_HUMAN (1-400): 2.25e-129: 405: 30.94		ARAP2_HUMAN (629-1477): 2.39e-88: 320: 16.89
+	Hs
		872705 EPHA4_HUMAN (74-487): 1.22e-123: 404: 24.82		RHG39_HUMAN (142-1095): 1.25e-90: 321: 15.98
+	Hs
		411807 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		ARAP2_HUMAN (629-1477): 2.39e-88: 320: 16.89
+	Mm
		975149 EPHA4_MOUSE (74-488): 8.21e-125: 407: 25.00		CHIN_MOUSE (624-1093): 2.34e-94: 314: 20.09
+	Hs
		64660 EPHB2_HUMAN (4-506): 2.6e-126: 413: 23.00		RHG32_HUMAN (703-1459): 1.27e-83: 306: 15.20
+	Hs
		253317 EPHB2_HUMAN (4-506): 2.6e-126: 413: 23.00		SRGP2_HUMAN (592-1477): 1.46e-84: 303: 15.39
+	Hs
		302630 YES_HUMAN (1-400): 5.47e-131: 410: 30.18		FA13A_HUMAN (880-1460): 8.49e-86: 305: 16.05
+	Hs
		64642 FYN_HUMAN (1-400): 2.25e-129: 405: 30.94		RHG32_HUMAN (703-1459): 1.27e-83: 306: 15.20
+	Hs
		64641 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		RHG32_HUMAN (703-1459): 1.27e-83: 306: 15.20
+	Hs
		64648 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		RHG32_HUMAN (703-1459): 1.27e-83: 306: 15.20
+	Hs
		411763 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		RHG17_HUMAN (780-1445): 4.76e-78: 280: 15.48
+	Hs
		523026 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		RHG17_HUMAN (780-1445): 4.76e-78: 280: 15.48
+	Hs
		411755 LCK_HUMAN (1-398): 3.4e-128: 401: 30.33		RHG21_HUMAN (31-956): 3.38e-69: 260: 21.56
+	Hs
		522938 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		RHG01_HUMAN (897-1069): 6.73e-21: 99.4: 32.57