HitPredict

Interactor 1: CNTP1 (O54991)
Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin)
Gene: Cntnap1

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0050885 - neuromuscular process controlling balance GO:0098978 - glutamatergic synapse
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1385 Mm			1 724
+	Dm
		1181889 NRX4_DROME (24-1320): 0: 636: 26.50		Q7KT16_DROME (230-719): 2.16e-93: 305: 22.51
+	Mm
		1143490 NRX1A_MOUSE (366-598): 4.93e-23: 109: 19.26		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Rn
		677793 NRX2A_RAT (1076-1374): 8.24e-22: 105: 13.19		DLG4_RAT (1-724): 0: 671: 99.45
+	Dm
		116474 NRX4_DROME (24-1320): 0: 636: 26.50		M9PJD0_DROME (14-159): 2.78e-15: 82.4: 17.81
+	Dm
		53139 NRX4_DROME (24-1320): 0: 636: 26.50		A1Z8G0_DROME (18-332): 2.6e-15: 81.7: 15.03
+	Dm
		1214755 Q8IQH0_DROME (24-1320): 0: 615: 26.57		Q9W3H7_DROME (21-160): 1.21e-17: 89.8: 17.86
+	Dm
		1214751 Q8IQH0_DROME (24-1320): 0: 615: 26.57		Q8T5S9_DROME (18-152): 1.9e-15: 82.1: 21.43
+	Rn
		991056 NRX3A_RAT (1081-1340): 9.31e-23: 108: 12.28		CSKP_RAT (31-271): 2.11e-20: 98.6: 14.80
+	Rn
		1144068 NRX2A_RAT (1076-1374): 8.24e-22: 105: 13.19		CSKP_RAT (31-271): 2.11e-20: 98.6: 14.80
+	Hs
		129803 AGRIN_HUMAN (140-335): 2.18e-20: 100: 18.39		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		159287 CNTP2_HUMAN (1061-1359): 7.09e-15: 82.3: 14.83		CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43
+	Rn
		1144066 NRX1A_RAT (178-358): 1.84e-13: 77.7: 20.31		CSKP_RAT (31-271): 2.11e-20: 98.6: 14.80
+	Hs
		159262 CNTP4_HUMAN (1085-1353): 4.76e-13: 76.5: 15.52		CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43
+	Mm
		1321671 CNTP2_MOUSE (1061-1359): 4.81e-16: 86.2: 16.09		MPP2_MOUSE (2-189): 2.31e-16: 84.8: 15.71
+	Dm
		422955 NOTCH_DROME (811-1294): 5.58e-15: 83.1: 9.70		Q9W3H8_DROME (21-160): 5.66e-17: 87.8: 17.86
+	Hs
		1050420 CNTP2_HUMAN (1061-1359): 7.09e-15: 82.3: 14.83		MPP2_HUMAN (2-189): 1.25e-16: 85.9: 15.71
+	Dm
		1096790 NRX1_DROME (713-966): 2.73e-15: 83.9: 14.54		CSKP_DROME (34-161): 1.19e-13: 76.7: 14.73