HitPredict

Interactor 1: NCK2 (O55033)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: HNRPK (P61979)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K)
Gene: Hnrnpk

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	11557983
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 380 Mm			1 463
+	Hs
		209022 NCK2_HUMAN (1-380): 1.15e-93: 287: 96.05		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		904174 ITSN2_HUMAN (5-300): 7.23e-34: 135: 18.60		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		903956 ITSN1_HUMAN (4-305): 7.9e-24: 105: 15.78		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		442807 HCK_HUMAN (2-205): 1.34e-22: 101: 19.42		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		412116 FYN_HUMAN (7-205): 4.93e-22: 99.5: 12.68		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		522880 SRC_HUMAN (7-120): 5.83e-16: 81.3: 18.10		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Mm
		904258 GRB2_MOUSE (1-60): 1.6e-16: 79.5: 29.51		HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00
+	Hs
		903873 GRB2_HUMAN (3-60): 3.75e-16: 78.7: 31.03		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Rn
		904380 GRB2_RAT (3-60): 3.75e-16: 78.7: 31.03		HNRPK_RAT (1-463): 1.31e-129: 385: 100.00
+	Hs
		903901 ITK_HUMAN (2-129): 2.34e-13: 73.3: 23.85		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Mm
		643095 P85A_MOUSE (24-379): 1.32e-31: 128: 12.57		PCBP2_MOUSE (23-147): 1.3e-12: 70.9: 21.09
+	Hs
		655435 P85A_HUMAN (24-379): 4.46e-31: 126: 12.57		FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29
+	Hs
		655379 P85A_HUMAN (24-379): 4.46e-31: 126: 12.57		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		522876 SRC_HUMAN (7-120): 5.83e-16: 81.3: 18.10		PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24
+	Hs
		522998 SRC_HUMAN (7-120): 5.83e-16: 81.3: 18.10		PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21
+	Hs
		924755 GRB2_HUMAN (3-60): 3.75e-16: 78.7: 31.03		FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29
+	Hs
		924788 GRB2_HUMAN (3-60): 3.75e-16: 78.7: 31.03		FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41
+	Hs
		924908 GRB2_HUMAN (3-60): 3.75e-16: 78.7: 31.03		IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57